{"id":914,"date":"2024-11-13T19:51:31","date_gmt":"2024-11-13T10:51:31","guid":{"rendered":"https:\/\/h2-portal.com\/?p=914"},"modified":"2024-11-14T08:28:01","modified_gmt":"2024-11-13T23:28:01","slug":"%e5%bf%83%e5%81%9c%e6%ad%a2%e5%be%8c%e3%81%ae%e8%84%b3%e3%82%92%e5%ae%88%e3%82%8b-%e6%b0%b4%e7%b4%a0%e3%82%ac%e3%82%b9%e3%81%ae%e9%a9%9a%e7%95%b0%e3%81%ae%e6%b2%bb%e7%99%82%e5%8a%b9%e6%9e%9c","status":"publish","type":"post","link":"https:\/\/h2-portal.com\/?p=914","title":{"rendered":"\u5fc3\u505c\u6b62\u5f8c\u306e\u8133\u3092\u5b88\u308b | \u6c34\u7d20\u30ac\u30b9\u306e\u9a5a\u7570\u306e\u6cbb\u7642\u52b9\u679c"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

\u306f\u3058\u3081\u306b<\/h2>\n\n\n\n

\u5fc3\u505c\u6b62\u306f\u7a81\u7136\u306e\u5fc3\u81d3\u6a5f\u80fd\u505c\u6b62\u3092\u6307\u3057\u3001\u6551\u547d\u306b\u306f\u8fc5\u901f\u306a\u5fc3\u80ba\u8607\u751f\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u8607\u751f\u5f8c\u306e\u8133\u640d\u50b7\u3084\u591a\u81d3\u5668\u4e0d\u5168\u306f\u4f9d\u7136\u3068\u3057\u3066\u6df1\u523b\u306a\u8ab2\u984c\u3067\u3042\u308a\u3001\u3053\u308c\u3089\u306e\u5f8c\u907a\u75c7\u306f\u60a3\u8005\u306e\u793e\u4f1a\u5fa9\u5e30\u3092\u56f0\u96e3\u306b\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u72b6\u614b\u306f\u300c\u5fc3\u505c\u6b62\u5f8c\u75c7\u5019\u7fa4 (Post Cardiac Arrest Syndrome, PCAS)\u300d\u3068\u547c\u3070\u308c\u307e\u3059\u3002\u5f93\u6765\u306e\u6cbb\u7642\u6cd5\u3067\u3042\u308b\u4f4e\u4f53\u6e29\u7642\u6cd5\u306f\u4e00\u5b9a\u306e\u52b9\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u9650\u754c\u304c\u3042\u308b\u305f\u3081\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8fd1\u5e74\u3001\u6c34\u7d20\u30ac\u30b9\u5438\u5165\u7642\u6cd5\u304c\u5f37\u529b\u306a\u8133\u4fdd\u8b77\u4f5c\u7528\u3092\u6301\u3064\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3001\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u6c34\u7d20\u30ac\u30b9\u306e\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u3001\u52d5\u7269\u5b9f\u9a13\u3084\u81e8\u5e8a\u7814\u7a76\u306e\u6210\u679c\u3001\u5b89\u5168\u6027\u3001\u305d\u3057\u3066\u4eca\u5f8c\u306e\u5c55\u671b\u306b\u3064\u3044\u3066\u8a73\u8ff0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u5fc3\u505c\u6b62\u5f8c\u75c7\u5019\u7fa4\u3068\u9178\u5316\u30b9\u30c8\u30ec\u30b9<\/h2>\n\n\n\n

\u5fc3\u505c\u6b62\u5f8c\u306b\u81ea\u5df1\u5fc3\u62cd\u304c\u518d\u958b\u3057\u3066\u3082\u3001\u8133\u3084\u5fc3\u81d3\u3092\u542b\u3080\u81d3\u5668\u306b\u6df1\u523b\u306a\u5f8c\u907a\u75c7\u304c\u6b8b\u308b\u5834\u5408\u304c\u591a\u304f\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u4e3b\u306a\u539f\u56e0\u306f\u3001\u8840\u6d41\u304c\u518d\u958b\u3059\u308b\u969b\u306b\u767a\u751f\u3059\u308b\u865a\u8840\u518d\u704c\u6d41\u969c\u5bb3\u3067\u3059\u3002\u3053\u306e\u969c\u5bb3\u3067\u306f\u3001\u6d3b\u6027\u9178\u7d20\u7a2e (Reactive Oxygen Species, ROS) \u304c\u904e\u5270\u306b\u751f\u6210\u3055\u308c\u3001\u7d30\u80de\u819c\u3001DNA\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306a\u3069\u3092\u653b\u6483\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u30e9\u30b8\u30ab\u30eb (\u00b7OH) \u306f\u975e\u5e38\u306b\u9ad8\u3044\u9178\u5316\u529b\u3092\u6301\u3061\u3001\u7d30\u80de\u6b7b\u3084\u708e\u75c7\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u8133\u306f\u9178\u7d20\u4f9b\u7d66\u306b\u975e\u5e38\u306b\u654f\u611f\u306a\u5668\u5b98\u3067\u3042\u308a\u3001\u3053\u3046\u3057\u305f\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u306e\u3067\u3059\u3002\u5f93\u6765\u306e\u6cbb\u7642\u6cd5\u3067\u3042\u308b\u4f4e\u4f53\u6e29\u7642\u6cd5\u306f\u3001\u3053\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u304c\u3042\u308b\u3082\u306e\u306e\u3001\u5b8c\u5168\u306a\u9632\u5fa1\u306b\u306f\u81f3\u3089\u306a\u3044\u305f\u3081\u3001\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u5fc5\u8981\u6027\u304c\u9ad8\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u6c34\u7d20\u30ac\u30b9\u306e\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0<\/h2>\n\n\n\n

\u6c34\u7d20\u30ac\u30b9 (H\u2082) \u306f\u3001\u5206\u5b50\u91cf\u304c\u5c0f\u3055\u304f\u751f\u4f53\u5185\u3067\u306e\u62e1\u6563\u6027\u304c\u9ad8\u3044\u7279\u6027\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u30022007\u5e74\u306b\u65e5\u672c\u533b\u79d1\u5927\u5b66\u306e\u592a\u7530\u6210\u7537\u6559\u6388\u3089\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u6c34\u7d20\u30ac\u30b9\u304c\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u30e9\u30b8\u30ab\u30eb (\u00b7OH) \u3084\u30da\u30eb\u30aa\u30ad\u30b7\u30ca\u30a4\u30c8\u30e9\u30a4\u30c8 (ONOO\u207b) \u306a\u3069\u306e\u5f37\u529b\u306a\u9178\u5316\u5264\u3092\u9078\u629e\u7684\u306b\u9664\u53bb\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u9078\u629e\u7684\u306a\u6297\u9178\u5316\u4f5c\u7528\u306b\u3088\u3063\u3066\u3001\u6c34\u7d20\u30ac\u30b9\u306f\u751f\u7406\u7684\u306a\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306b\u5fc5\u8981\u306aROS\u306b\u306f\u5f71\u97ff\u3092\u4e0e\u3048\u305a\u3001\u904e\u5270\u306a\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u307f\u3092\u52b9\u679c\u7684\u306b\u6291\u5236\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u6c34\u7d20\u5206\u5b50\u306f\u7d30\u80de\u819c\u3092\u5bb9\u6613\u306b\u901a\u904e\u3057\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3084\u6838\u5185\u306b\u3082\u8fc5\u901f\u306b\u5230\u9054\u3059\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u5185\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u7279\u6027\u304c\u3001\u6c34\u7d20\u30ac\u30b9\u306e\u8133\u4fdd\u8b77\u4f5c\u7528\u3092\u88cf\u4ed8\u3051\u308b\u91cd\u8981\u306a\u30dd\u30a4\u30f3\u30c8\u3067\u3059\u3002<\/p>\n\n\n\n

\u52d5\u7269\u5b9f\u9a13\u306b\u3088\u308b\u52b9\u679c\u306e\u691c\u8a3c<\/h2>\n\n\n\n

\u52d5\u7269\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u306f\u3001\u6c34\u7d20\u30ac\u30b9\u306e\u9855\u8457\u306a\u52b9\u679c\u304c\u6570\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30e9\u30c3\u30c8\u3092\u7528\u3044\u305f\u5fc3\u505c\u6b62\u30e2\u30c7\u30eb\u3067\u306f\u3001\u5fc3\u505c\u6b62\u5f8c\u306b2\uff05\u306e\u6c34\u7d20\u30ac\u30b9\u3092\u5438\u5165\u3055\u305b\u308b\u3068\u3001\u795e\u7d4c\u5b66\u7684\u4e88\u5f8c\u306e\u6539\u5584\u3068\u751f\u5b58\u7387\u306e\u5411\u4e0a\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u751f\u5b58\u7387\u306f\u3001\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u7fa4\u306e30\uff05\u306b\u5bfe\u3057\u3001\u6c34\u7d20\u30ac\u30b9\u5438\u5165\u7fa4\u3068\u4f4e\u4f53\u6e29\u7642\u6cd5\u7fa4\u306770\uff05\u306b\u9054\u3057\u3001\u4e21\u65b9\u3092\u4f75\u7528\u3059\u308b\u306880\uff05\u8fd1\u304f\u306b\u6539\u5584\u3057\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u795e\u7d4c\u8131\u843d\u30b9\u30b3\u30a2 (Neurological Deficit Score, NDS) \u306b\u3088\u308b\u8a55\u4fa1\u3067\u3082\u3001\u4f4e\u4f53\u6e29\u7642\u6cd5\u3068\u540c\u7b49\u306e\u6539\u5584\u52b9\u679c\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u5225\u306e\u7814\u7a76\u3067\u306f\u5fc3\u505c\u6b62\u5f8c\u306e\u30d6\u30bf\u306b\u6c34\u7d20\u30ac\u30b9\u3092\u5438\u5165\u3055\u305b\u305f\u7d50\u679c\u3001\u8133\u5185\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u30de\u30fc\u30ab\u30fc\u304c\u5927\u5e45\u306b\u6e1b\u5c11\u3057\u3001\u795e\u7d4c\u6a5f\u80fd\u306e\u56de\u5fa9\u304c\u4fc3\u9032\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u52d5\u7269\u5b9f\u9a13\u306e\u6210\u679c\u306f\u3001\u6c34\u7d20\u30ac\u30b9\u304c\u8133\u640d\u50b7\u3092\u8efd\u6e1b\u3057\u3001\u6a5f\u80fd\u56de\u5fa9\u3092\u52a9\u3051\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u81e8\u5e8a\u7814\u7a76\u306e\u9032\u5c55<\/h2>\n\n\n\n

\u52d5\u7269\u5b9f\u9a13\u306e\u6210\u529f\u3092\u53d7\u3051\u3066\u3001\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u81e8\u5e8a\u7814\u7a76\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u56fd\u5185\u306e\u591a\u65bd\u8a2d\u5171\u540c\u7814\u7a76\u3067\u306f\u3001\u5fc3\u505c\u6b62\u5f8c\u306e\u60a3\u8005\u306b\u6c34\u7d20\u30ac\u30b9\u3092\u5438\u5165\u3055\u305b\u305f\u3068\u3053\u308d\u300190\u65e5\u5f8c\u306e\u795e\u7d4c\u5b66\u7684\u4e88\u5f8c\u304c\u5927\u5e45\u306b\u6539\u5584\u3057\u3001\u793e\u4f1a\u5fa9\u5e30\u7387\u304c\u5287\u7684\u306b\u5411\u4e0a\u3057\u307e\u3057\u305f\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u5f8c\u907a\u75c7\u304c\u5168\u304f\u306a\u3044\u5b8c\u5168\u306a\u793e\u4f1a\u5fa9\u5e30\u7387\u304c\u3001\u6a19\u6e96\u6cbb\u7642\u7fa4\u306e21\uff05\u306b\u5bfe\u3057\u3001\u6c34\u7d20\u30ac\u30b9\u7fa4\u3067\u306f46\uff05\u306b\u9054\u3057\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u6025\u6027\u5fc3\u7b4b\u6897\u585e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u7d4c\u76ae\u7684\u51a0\u52d5\u8108\u5f62\u6210\u8853\u4e2d\u306b\u6c34\u7d20\u30ac\u30b9\u3092\u5438\u5165\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u5fc3\u7b4b\u306e\u640d\u50b7\u3092\u8efd\u6e1b\u3057\u3001\u5fc3\u6a5f\u80fd\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u6c34\u7d20\u30ac\u30b9\u5438\u5165\u7642\u6cd5\u306f\u5fc3\u505c\u6b62\u5f8c\u75c7\u5019\u7fa4\u306e\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u975e\u5e38\u306b\u6709\u671b\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3059\u3002<\/p>\n\n\n\n

\u6c34\u7d20\u30ac\u30b9\u5438\u5165\u306e\u5b89\u5168\u6027<\/h2>\n\n\n\n

\u6c34\u7d20\u30ac\u30b9\u306f\u3001\u7121\u8272\u30fb\u7121\u81ed\u3067\u3042\u308a\u3001\u4eba\u4f53\u306b\u5bfe\u3059\u308b\u6bd2\u6027\u306f\u6975\u3081\u3066\u4f4e\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9ad8\u6fc3\u5ea6\u306e\u6c34\u7d20\u30ac\u30b9\u306f\u53ef\u71c3\u6027\u3092\u6301\u3061\u307e\u3059\u304c\u3001\u81e8\u5e8a\u3067\u4f7f\u7528\u3055\u308c\u308b1\u301c4\uff05\u306e\u6fc3\u5ea6\u3067\u306f\u7206\u767a\u306e\u5371\u967a\u6027\u304c\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002\u307e\u305f\u3001NASA\uff08\u30a2\u30e1\u30ea\u30ab\u822a\u7a7a\u5b87\u5b99\u5c40\uff09\u3082\u3001\u6c34\u7d20\u30ac\u30b9\u304c\u4eba\u4f53\u306b\u7121\u5bb3\u3067\u3042\u308b\u3068\u5831\u544a\u3057\u3066\u304a\u308a\u3001\u6df1\u6d77\u6f5c\u6c34\u306b\u3082\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u307e\u3067\u306e\u81e8\u5e8a\u7814\u7a76\u3067\u3082\u6c34\u7d20\u30ac\u30b9\u5438\u5165\u306b\u95a2\u9023\u3059\u308b\u91cd\u5927\u306a\u526f\u4f5c\u7528\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u4ed6\u306e\u6297\u9178\u5316\u7269\u8cea\u3068\u7570\u306a\u308a\u3001\u6c34\u7d20\u30ac\u30b9\u306f\u7d30\u80de\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u59a8\u3052\u306a\u3044\u305f\u3081\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u306e\u304c\u5927\u304d\u306a\u5229\u70b9\u3067\u3059\u3002<\/p>\n\n\n\n

\u307e\u3068\u3081<\/h2>\n\n\n\n

\u6c34\u7d20\u30ac\u30b9\u5438\u5165\u7642\u6cd5\u306f\u3001\u5fc3\u505c\u6b62\u5f8c\u306e\u91cd\u7be4\u306a\u8133\u640d\u50b7\u3092\u9632\u3050\u753b\u671f\u7684\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u9078\u629e\u7684\u306b\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u795e\u7d4c\u6a5f\u80fd\u306e\u56de\u5fa9\u3092\u4fc3\u9032\u3057\u3001\u793e\u4f1a\u5fa9\u5e30\u7387\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002\u4eca\u5f8c\u306e\u3055\u3089\u306a\u308b\u7814\u7a76\u306b\u3088\u308a\u3001\u5fc3\u505c\u6b62\u5f8c\u75c7\u5019\u7fa4\u306e\u6a19\u6e96\u6cbb\u7642\u3068\u3057\u3066\u78ba\u7acb\u3055\u308c\u308b\u65e5\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

\u53c2\u7167\u6587\u732e<\/h4>\n\n\n\n
    \n
  1. \u300c\u5fc3\u80ba\u505c\u6b62\u8607\u751f\u5f8c\u81d3\u5668\u969c\u5bb3\u6291\u5236\u300d(\u4f50\u91ce\u5143\u662d, 2016)<\/li>\n\n\n\n
  2. \u300c\u6c34\u7d20\u306e\u81e8\u5e8a\u5fdc\u7528\u300d(\u9234\u6728\u660c, 2023)<\/li>\n\n\n\n
  3. \u300c\u6c34\u7d20\u533b\u5b66\u7dcf\u8aac\u300d(\u592a\u7530\u6210\u7537, 2015)<\/li>\n\n\n\n
  4. “Hydrogen Gas Inhalation Therapy and Its Application in Post-Cardiac Arrest Syndrome: A Review of Clinical Evidence” (International Journal of Molecular Sciences, 2021)<\/li>\n\n\n\n
  5. “Molecular Hydrogen as a Selective Antioxidant: A Clinical and Experimental Review” (Journal of Medical Gas Research, 2020)<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

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